Biomaterial development for oral and maxillofacial bone regeneration
Lindsay S. Karfeld-Sulzer, Franz E. Weber,
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( Lindsay S. Karfeld-Sulzer ) - University Hospital Zurich Department of Cranio-Maxillofacial and Oral Surgery Oral Biotechnology and Bioengineering
( Franz E. Weber ) - University Hospital Zurich Department of Cranio-Maxillofacial and Oral Surgery Oral Biotechnology and Bioengineering
KMID : 0355620120380050264
Abstract
Many oral and maxillofacial bone defects are not self-healing. Guided bone regeneration (GBR), which uses a barrier membrane to prevent the soft tissues from invading the defect to enable slower-growing bone cells to penetrate the area, was developed as a therapy in the 1980s. Although there has been some success with GBR in some clinical situations, better treatments are needed. This review discusses the concept of GBR focusing on bioactive membranes that incorporate osteoconductive materials, growth factors and cells for improved oral and maxillofacial bone regeneration.
키워드
Bone; Guided bone regeneration; Barrier membrane; Bone substitutes; Drug delivery; Stem cells
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